Publications

Danielsson, B.E., et. al, Nuclear lamina strain states revealed by intermolecular force biosensor, Nature Communications, Jun. 2023. https://doi.org/10.1038/s41467-023-39563-6

Narayanan, V., et. al, Rho activation drives luminal collapse and eversion in epithelial acini, Biophysical Journal, Jan. 2023. https://doi.org/10.1016/j.bpj.2023.01.005

Bejar-Padilla, V., et. al, α–Catenin-dependent vinculin recruitment to adherens junctions is antagonistic to focal adhesions, Molecular Biology of the Cell, Sep. 2022. https://doi.org/10.1091/mbc.E22-02-0071

Danielsson, B.E., et. al, Chromatin condensation regulates endothelial cell adaptation to shear stress, Molecular Biology of the Cell, Sep. 2022. https://doi.org/10.1091/mbc.E22-02-0064

Denis, K.B., et. al, The LINC complex is required for endothelial cell adhesion and adaptation to shear stress and cyclic stretch., Molecular Biology of the Cell, Aug. 2021. https://doi.org/10.1091/mbc.E20-11-0698

Danielsson, B.E., et. al, Progerin-expressing endothelial cells are unable to adapt to shear stress., Biophysical Journal, Feb. 2021. https://doi.org/10.1016/j.bpj.2022.01.004

Padhi, A., Danielsson, B.E., et al., Cell Fragment Formation, Migration, and Force Exertion on Extracellular Mimicking Fiber Nanonets. Advanced Biology, Mar. 2021. https://doi.org/10.1002/adbi.202000592

Danielsson, B.E., Tieu, K.V., et al., Lamin microaggregates lead to altered mechanotransmission in progerin-expressing cells. Nucleus, vol. 11, 1., pp. 194-204. Aug. 2020. doi: https://doi.org/10.1080/19491034.2020.18029

Narayanan, V, et al., Osmotic Gradients in Epithelial Acini Increase Mechanical Tension across E-Cadherin, Drive Morphogenesis, and Maintain Homeostasis. Current Biology, vol. 30, 24 Feb. 2020, pp. 1–10.,https://doi.org/10.1016/j.cub.2019.12.025.

 Bui, Justin, et al. Mechanochemical Coupling and Junctional Forces during Collective Cell Migration. Biophysical Journal , vol. 117, no. 1, 9 July 2019, p. 170183., doi:10.1101/558452.

Zhang et al., Mechanical Stabilization of the Glandular Acinus by Linker of Nucleoskeleton and Cytoskeleton Complex, Current Biology (2019), https://doi.org/10.1016/j.cub.2019.07.021 

Mayer, C.R., et al. Characterization of 3D Printed Stretching Devices for Imaging Force Transmission in Live-Cells. Cellular and Molecular Bioengineering. vol. 12, 4., pp289-300, Aug 2019. 

Mohan, A, et al. Spatial Proliferation of Epithelial Cells Is Regulated by E-Cadherin Force. Biophysical Journal. vol. 115, no. 5, 4 Sept. 2018,853–864.

Baddam SR, Arsenovic PT, Narayanan V, et al. The Desmosomal Cadherin Desmoglein-2 Experiences Mechanical Tension as Demonstrated by a FRET-Based Tension Biosensor Expressed in Living Cells. Cells. 2018;7(7):66. 2018 Jun 26. 

Conway DE, Coon BG, Budatha M, et al. VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN. Curr Biol. 2017;27(14):2219-2225.e5.

Arsenovic PT, Bathula K, Conway DE.A Protocol for Using Förster Resonance Energy Transfer (FRET)-force Biosensors to Measure Mechanical Forces across the Nuclear LINC Complex. J Vis Exp. 2017;(122):54902. 

Arsenovic, Paul T., et al. SensorFRET: A Standardless Approach to Measuring Pixel-Based Spectral Bleed-through and FRET Efficiency Using Spectral Imaging. Scientific Reports, vol. 7, no. 1, 2017.

Crabb, Edward B., et al. The Impact of Laminar and Oscillatory Shear Stress on Cellular Adhesion Molecule Expression in HUVEC. Medicine & Science in Sports & Exercise, vol. 49, 2 June 2017, pp. 807–808.

Lagendijk AK, Gomez GA, Baek S, et al. Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish. Nat Commun. 2017;8(1):1402. 2017 Nov 10. 

Baddam, Sindora, et al. Desmosomes Are Subject to Mechanical Load. Biophysical Journal, vol. 112, no. 3, 3 Feb. 2017. 

Brenner MD, Zhou R, Conway DE, Lanzano L, Gratton E, Schwartz MA, Ha T.  Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing.  Nano Lett. 2016 Mar 9;16(3):2096-102.  

Arsenovic PT,* Ramachandran I,* Bathula K, Zhu R, Narang JD, Noll NA, Lemmon CA, Gundersen GG, Conway DE.  Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension. Biophys J. 2016 Jan 5;110(1):34-43.   * denotes co-first authorship  

Daneshjou N, Sieracki N, van Nieuw Amerongen GP, Conway DE, Schwartz MA, Komarova YA, Malik AB.  Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction.  Journal of Cell Biology, 2015 208(1):  23-32.  

Tornavaca O, Chia M, Dufton N, Almagro LO, Conway DE, Randi AM, Schwartz MA, Matter K, Balda MS.  ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis and barrier formation.  Journal of Cell Biology, 2015 208(6):  821-38.  

Conway DE, Schwartz MA.  Mechanotransduction of shear stress occurs through changes in VE-cadherin and PECAM-1 tension:  Implications for cell migration.  Cell Adhesion and Migration.  Cell Adhesion & Migration.  2015;9(5):335-9.  

Conway DE, Schwartz MA.  Flow-dependent cellular mechanotransduction in atherosclerosis.  J Cell Sci. 2013 126(Pt 22):5101-9.  

Conway DE, Breckenridge MT, Hinde E, Graton E, Chen CS, Schwartz MA.  Fluid shear stress modulates mechanical tension across VE-cadherin and PECAM-1 in endothelial cells.  Current Biology, 2013 23(11):  1024-30.  

DE Conway, SG Eskin, LV McIntire. Effects of Mechanical Forces on Cells and Tissues (The Liquid–Cell Interface). Biomaterials Science, 2013; (Third Edition), 474-487.

Conway D, Schwartz MA.  Lessons from the endothelial junctional mechanosensory complex.  F1000 Biol Rep, 2012 4(1).  

Conway DE, Lee S, Eskin SG, Shah AK, Jo H, McIntire LV.  Endothelial Metallothionein Expression and Intracellular Free Zinc Levels are Regulated by Shear Stress.  Am J Physiol Cell Physiol, 2010 Dec;299(6):C1461-7.  

Conway DE, Williams MR, Eskin SG, McIntire LV.  Reversing shear stress promotes a more inflammatory and proliferative phenotype in endothelial cells.  Am J Physiol Heart Circ Physiol, 2010 298(2):H367-74.  

Conway DE, Sakurai Y, Weiss D, Vega JD, Taylor WR, Jo H, Eskin SG, Marcus CB, McIntire LV.  Expression of CYP1A1 and CYP1B1 in human endothelial cells is regulated by fluid shear stress.  Cardiovascular Research, 2009;81(4):669-677.  

Yee A, Bosworth KA, Conway DE, Eskin SG, McIntire LV.  Gene expression of endothelial cells under pulsatile non-reversing vs. steady shear stress; comparison of nitric oxide production.  Annals of Biomedical Engineering.  2008;36(4):571-9.  

Temenoff JS, Park H, Jabbari E, Conway DE, Sheffield TL, Ambrose CG, Mikos AG. Thermally cross-linked oligo(poly(ethylene glycol) fumarate) hydrogels support osteogenic differentiation of encapsulated marrow stromal cells in vitro. Biomacromolecules. 2004;5(1):5-10.  

Temenoff JS, Shin H, Conway DE, Engel PS, Mikos AG. In vitro cytotoxicity of redox radical initiators for cross-linking of oligo(poly(ethylene glycol) fumarate) macromers. Biomacromolecules. 2003;4(6):1605-1613.